p53_monoclonal_antibodies

Name	Epitope Location	Antigen used for immunization	Isotype	Other species recognition	WB	IP	Comercial availability
B17	16-25	Human p53	IgG2a	Yes	Yes	Yes	No
X77	16-25	Xenopus p53	IgG1	Yes	Yes	Yes	No
X73	16-25	Xenopus p53	IgG1	Yes	Yes	Yes	No
X18	16-25	Xenopus p53	IgG1	Yes	Yes	Yes	No
C36	16-30	Human p53	IgG1	Yes	Yes	Yes	No
X87	16-30	Xenopus p53	IgG1	Yes	Yes	Yes	No
X44	16-30	Xenopus p53	IgG1	Yes	Yes	Yes	No
X61	16-30	Xenopus p53	IgG1	Yes	Yes	Yes	No
X91	16-30	Xenopus p53	IgG1	Yes	Yes	Yes	No
X29	233-363	Xenopus p53	IgG1	No	Yes	Yes	No
X57	233-363	Xenopus p53	IgG1	No	Yes	Yes	No
X20	233-363	Xenopus p53	IgG1	No	Yes	Yes	No
X36	349-360	Xenopus p53	IgG1	No	Yes	Yes	No
X10	349-360	Xenopus p53	IgG1	No	Yes	Yes	No
X65b	349-360	Xenopus p53	IgG1	No	Yes	Yes	No
X45	349-360	Xenopus p53	IgG1	No	Yes	Yes	No
X86	349-360	Xenopus p53	IgG1	No	Yes	Yes	No
X89	349-360	Xenopus p53	IgG1	No	Yes	Yes	No
X85	349-363	Xenopus p53	IgG1	No	Yes	Yes	No

References

12 Legros Y, Lafon C and Soussi T (1994) Linear antigenic sites defined by the B-cell response to human p53 are localized predominantly in the amino and carboxy-termini of the protein. Oncogene 9 : 2071-2076.
13 Legros Y, Meyer A, Ory K and Soussi T (1994) Mutations in p53 produce a common conformational effect that can be detected with a panel of monoclonal antibodies directed toward the central part of the p53 protein. Oncogene 9 : 3689-3694.
19 Hardy-Bessard AC, Garay E, Lacronique V, Legros Y, Demarquay C, Houque A, Portefaix JM, Granier C and Soussi T (1998) Regulation of the specific DNA binding activity of Xenopus laevis p53 : evidence for conserved regulation through the carboxy-terminus of the protein. Oncogene 16 : 883-890.