p53 Information

p53 information

p53 story

p53 monoclonal antibodies

p53 pathways

p53 gene

p53 protein(s)

mdm family

p63/p73 protein(s)

p53 evolution

p53 polymorphism

p53 and cancer

mouse models

ASPP family




p53 Polymorphisms


Several polymorphims have been identified in the TP53 gene. Some of them have been analyzed on a large scale population and their distribution in the human population is well known (Codon 72 (Arg/Pro), the duplication of 16pb in intron 3 and the intron 6 G/A SNP). Other polymorphisms have been described rarely and their signification remain to be analyzed. Before using any of these polymorphisms for clinical studies, it is strongly suggested to check their frequency in a normal population. Very rare polymorphisms or polymorphisms described only in a single publication are not listed here.


You can click the ID number to access more information on each SNP. Only data from SNP with >5% frequency are shown

More p53 SNP can be found:

The SNP500 Cancer database
The TP53 gencard





Home | Our Work |p53 Info| p53 Database | p53 Link | Contact us