Our Work

Our work

p53 structure

Xenopus p53

p53 in Lung cancer

p53 in Breast cancer

p53 antibodies in cancer

p73 antibodies in cancer

Publications of the lab

Thierry Soussi, PhD
Professor of Molecular Biology

UNIVERSITY P.M. CURIE, PARIS VI
FRANCE



and

CANCER CENTRUM KAROLINSKA
KAROLINSKA INSTITUTET
STOCKHOLM, SWEDEN

The main goal of our laboratory is to elucidate the biochemical and biological functions of the p53 tumor suppressor gene and how it is transformed into a dominant oncogene in human cancer.

Our work can be divided in two areas:

Understanding the structure - function relationship of the p53 protein

Define new tools and new targets of clinical value to improve cancer diagnosis