p53 Information

p53 information

p53 story

p53 monoclonal antibodies

p53 pathways

p53 gene

p53 protein(s)

mdm family

p63/p73 protein(s)

p53 evolution

p53 polymorphism

p53 and cancer

mouse models

ASPP family


 p53 gene

The TP53 gene is localized on chromosome 17 (short arm, 17p13), a region that is frequently deleted in human cancer.



Organization of the human p53 gene. 22 000 bp; 11 exons (blue) coding for a 2.2 Kb mRNA. Translation begin in exon 2. Sizes of exons and introns are shown in bp.

See this page for more information on p53 isoforms





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