p53 Information

p53 information

p53 story

p53 monoclonal antibodies

p53 pathways

p53 gene

p53 protein(s)

modifications of p53

p53 isoforms

p53 domains

p53 partners

 

 

 

 



mdm family

p63/p73 protein(s)

p53 evolution

p53 polymorphism

p53 and cancer

mouse models

ASPP family

 

 

p53 domains

 

p53_protein

AD1: activation domain 1
AD2: activation domain 2
PRD: proline rich domain
NES: nuclear exclusion domain
HCD I: Highly Conserved Domain I

mdm2: binding sites for mdm2
RPA: binding site for RPA
p62/TfB1: binding site for p62/TfB1, a subunit of TFIIH

more information will be added in the upcoming weeks

 

 
 
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